Description
Product Characteristics: Function: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. Subcellular location: Cell membrane, Lipid-anchor âÄ° GPI-anchor Potential. Cell junction âÄ° synapse Tissue specificity: Expressed in the brain (at protein level).,Neurogenesis,Candidate plasticity gene 15 protein, NRN1, Cpg15
Target Information: This gene is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. [provided by RefSeq, Jul 2008]